The Truth About Opiate Withdrawal (from someone who has experienced it dozens of times!)

I was just reading an article on a major social media platform about opiate withdrawal.

A professional addiction expert was describing it like this: “You may experience some discomfort during withdrawal from opiates such as heroin. Symptoms including sneezing, stretching, occasional diarrhea and vomiting may occur…”

ARE YOU F*****G SERIOUS? “Occasional diarrhea and vomiting”??!!

Clearly the person who wrote this article had never experienced opiate withdrawal themselves.

And whatever college this addiction expert went to needs to update their curriculum because not only are they misinformed, but they are ignorant as hell too.

Out of the hundreds of times I detoxed, usually after months of slamming (IV use aka “shooting up”) heroin, hydromorphone, or oxycodone, lets just recall ONE of those times and do a comparison of what the addiction expert says to expect during withdrawal, and what the reality of withdrawal is.

I used to sell methamphetamine to pay for my opiate addiction/habit. I lived in a small town, and needless to say, I got busted several times doing that. Each time I got arrested, put me in a cell in the jail booking area to withdrawal.

One particular time, when I was working a ten balloon a day habit (heroin is sold in balloons sometimes for all of you that didn’t know) I began to get sick and the dread that comes with it – knowing from prior experience what’s coming – is nearly as bad as the physical symptoms themselves.

You start out sneezing, stretching, yawning and getting goose bumps all over and you begin to alternate between chills and cold sweats. Your nose begins to run. Some people get back spasms, and since I’m on the list of people that do absolutely everything the hard way, I had those every 30 seconds for the entire time as well

Then the nausea hits, usually closely followed by the drizzling shits – oh ya – the dreaded diarrhea.

And finally, no cake walk (not!) would be complete without the proverbial cherry on top so enter the projectile vomiting. Not just a little here or there. Repeatedly and more consistent than a bus on a transit schedule, that horrible, wretching vomiting.

There were moments I didn’t know whether to puke or shit and there were also moments I did BOTH and the option to choose was not up for discussion

This went on for about 5 days. At that point, I had lost nearly 15 lbs simply from losing every disgusting drop of bodily fluid you can dream up.

About that time the facility would medically clear me and send me to population where I had to play nice with the other girls while still feeling like death.

On the eleventh night I finally slept through the night, and from that point on it got gradually better.

I’ve said my piece – occasionally I have to set the record straight.

 

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Welcome to My Blog!

Ever since I began my recovery from Opiate Use Disorder its been my dream to help others do the same.

I got my life back and anybody else who finds themselves in the grip of Opiate Addiction can do the same. IT DOES NOT COST A DIME!

My goal with other addicts in turmoil is to guide the way to getting their lives back and I’m proud today to launch this blog and share my success with the world.

Stay tuned as everyday I will post stories, help, tips, lists and everything you can think of in support of fellow addicts.

I welcome and encourage comments, suggestions and questions. Please contact me at melificentdreams@gmail.com.

Have a blessed day today and everyday!!

What The F**k Are Opiate Agonists and Antagonists?

If you’ve been addicted to any form of opiods for very long then at some point you may have researched your addiction and heard the terms “opiate agonists” and “opiate antagonists”. If you were like me your next thought was What the fuck is that? Allow me to demystify them.

Agonists vs. Antagonists

An agonist is a drug that activates certain receptors in the brain. Full agonist opioids activate the opioid receptors in the brain fully resulting in the full opioid effect. Examples of full agonists are heroin, oxycodone, methadone, hydrocodone, morphine and others.

An antagonist is a drug that blocks opioids by attaching to the opioid receptors without activating them. Antagonists cause no opioid effect and block full agonist opioids. Examples are naltrexone and naloxone. Naloxone is sometimes used to reverse a heroin overdose.

Buprenorphine is a partial agonist, meaning it activates the opioid receptors in the brain, but to a much lesser degree than a full agonist.

Buprenorphine also acts as an antagonist, meaning it blocks other opioids, while allowing for some opioid effect of its own to suppress withdrawal symptoms and cravings.

How Opioids Work

Opioids attach to receptors in the brain. Normally these opioids are created naturally in the body. Once attached, they send signals to the brain which blocks pain, slows breathing, and has what I call “the warm fuzzy blanket feeling”. 

Opioids can activate receptors in the brain because their chemical structure mimics that of a natural neurotransmitter. This similarity in structure” fools” the brains receptors and allows the drug to lock onto and activate the nerve cells. Although these drugs mimic brain chemicals, the don’t activate nerve cells in the same way as a neurotransmitter, and they lead to abnormal messages being transmitted through the network.

Opioids target the brain’s reward system by flooding the circuit with dopamine. Dopamine is a neurotransmitter present in regions of the brain that regulate movement, emotion, cognition, motivation and feelings of pleasure. The overstimulation of this system, which rewards our natural behaviors, produces the euphoric effects sought by people who abuse drugs and causes them to repeat the behavior.

The Very Special People

Patients with chronic pain who require high doses of opioids to achieve pain relief show exceptionally high rates of defects of the cytochrome P450 (CYP450) enzyme system compared with the general population.

The CYP450 enzyme system is known to play an important role in the metabolism of opioids, and recent advances in genetic testing allow for the easy detection of defects to the enzymes.

A small percentage of the population literally don’t feel the effects of opioids due to this defect.

When I was laying in jail once withdrawaling from heroin I remember thinking, “Now why couldn’t I have been one of those people?